EliteFitness.com Bodybuilding ForumsIf this is your first visit, be sure to register before you can post: Registering gets you access to free supplement samples and special email sales for forum members only. Results 1 to 50g of anadrol 50mg a day. It is a dihydrotestosterone DHT derivative that is Alpha-Alkylated, meaning that it has been altered at the 17th carbon position to survive first pass through the liver from oral ingestion. From east german nva gear compiled in standard animal assay tests, Anadrol has been anadrol 50mg a day to be over three times as anabolic as testosterone, andarol less than half as androgenic.
How to Use Anadrol 50 | 8 Common Myths and Mistakes
If this is your first visit, be sure to register before you can post: Registering gets you access to free supplement samples and special email sales for forum members only. Results 1 to 2 of 2. It is a dihydrotestosterone DHT derivative that is Alpha-Alkylated, meaning that it has been altered at the 17th carbon position to survive first pass through the liver from oral ingestion.
From data compiled in standard animal assay tests, Anadrol has been shown to be over three times as anabolic as testosterone, but less than half as androgenic. However, real world results in humans demonstrate that Anadrol appears to be significantly more androgenic than the animal assays suggest. Oxymetholone was subsequently used in conditions such as geriatric debilitation, chronic underweight states, pre and post-operative preservation of lean mass, convalescence, gastrointestinal disease, osteoporosis, and general catabolic conditions.
The recommended dose for such uses was usually 2. While the stimulation of erythropoiesis is an effect of almost all anabolic steroids, Anadrol performs the task extremely well.
Anadrol has been shown to increase erythropoietin levels as much as 5 fold 1. As science and drug technology progressed, new treatments for anemia were brought forth that had more direct results with fewer side effects. Anadrol fell out of favor as an effective treatment for anemia and sales dropped. Syntex would stop production of Anadrol in the United States and many other countries, in In July , Syntex sold all rights to Anadrol in the U.
The other benefit to these patients with a wasting disease is that Anadrol is of course a very effective drug for promoting weight gain and thus combating wasting due to HIV. Anadrol Effects on the Body Anadrol is considered by many to be the most powerful oral steroid regularly available. Anadrol 50 users will find that it becomes active very quickly, producing dramatic strength, weight and size gains.
Novice Anadrol users can experience massive gains of up to pounds in as little as 6 to 8 weeks of use. As previously mentioned, Anadrol is not just used for incredible gains in size. Many strength plateaus have been broken by Anadrol users as well. To the benefit of those pushing the limits of their strength, a good portion of the gains from Anadrol will be from water retention. This helps provide some level of protection for connective tissues, as well as aiding muscle elasticity and contractility, which will hopefully decrease the chance of injury when lifting heavy weights.
Of course the user contemplating Anadrol use for this purpose should have taken Anadrol prior so he knows how his body reacts to the drug. It would be disastrous to use Anadrol improperly in this instance and end up looking bloated and smooth on stage. As one would expect, there have been many medical studies performed with Anadrol. The two oxymetholone groups also saw increases in 1 rep max of bench press and lat pull, with greater strength increases going to the larger dose group.
Interestingly, the placebo group saw a decrease in strength for these two exercises. The two Anadrol groups also saw greater fat reduction than the placebo group, with the larger decrease going to the larger dose group again. The pattern of changes among the groups for LBM, upper-body strength and decreased fat mass suggested that changes might be related to dose 2.
Anadrol was evaluated in a 30 week study and found to promote weight gain in patients with advanced HIV infection. The mean time to peak weight was This was merely from just walking at least one kilometer a day. Anadrol sounds like an incredible drug! Anadrol 50 can inhibit your body's natural hormone production and possibly negatively affect your blood lipid profile. Anadrol could cause water retention, headaches, and could also be hepatotoxic liver toxic.
And though one of the benefits touted by its original manufacturer Syntex is that it can be used to stimulate weight gain through increasing appetite, taking too much Anadrol may actually inhibit your appetite! Anadrol Side Effects Each user is going to be different in the side effects they may experience and how they react to a drug.
Some may be predisposed to conditions that Anadrol or other drugs could exacerbate such as hypertension High Blood Pressure—HBP or others. Anadrol causes notable estrogenic effects, and is often associated with reports of gynecomastia. But oxymetholone is derived from DHT so it cannot be aromatized converted to estrogen because it does not possess the structural capacity to do so. It has been speculated and assumed then that Anadrol is activating the progesterone receptor PR , however evidence is available that Anadrol showed no significant binding to the PR 8.
It has been speculated that Anadrol binds directly to the estrogen receptor ER since it cannot be converted to estrogen. But the properties of Anadrol make this a highly unlikely theory. The most plausible reason for the high apparent estrogenic activity of Anadrol is that a metabolite of the compound is binding to and activating the ER. If one is quite prone to gynecomastia, the best solution would probably be to avoid Anadrol use altogether. The 17aa alteration, which makes it possible for Anadrol to survive first pass through your liver, also makes it taxing on your liver.
We have seen human studies of up to 30 weeks in length without anyone dying! One study of 24 weeks length at a mg daily dose had only two out of 21 patients in the treatment group experience an elevation in serum liver enzymes. After 24 weeks on mg of Anadrol every day, the only adverse hepatic condition was elevated liver enzymes 4. It seems apparent that side effects from Anadrol can be managed and the drug can be used safely.
People are advised on message boards to limit their course of Anadrol to 4 weeks, while it seems even courses of weeks at 50mg, twice a day could be considered safe, especially when one uses a proper liver support supplement such as TUDCA , as all those who use oral AAS should.
While Anadrol is classified as an anabolic steroid showing low androgenic activity in assays, it does possess an undeniable androgenic effect, with possible androgenic side effects. Anadrol is already a dihydrotestosterone DHT based steroid, so it cannot directly convert to DHT via the 5-alpha reductase enzyme.
However, oxymetholone does exhibit some tendency to convert to dihydrotestosterone in the body. These effects are usually akin to higher doses. Women should avoid Anadrol due to its potential virilizing effects which include, deepening of the voice, abnormal menstruation, hirsutism male pattern hair growth in women , changes in skin texture, and clitoral enlargement. Anadrol has been shown to have some effects on plasma lipids, most notably its effect on plasma HDL-cholesterol concentrations.
A user can attempt to alleviate this by supplementing with fish oils up to grams a day and a dietary supplement formulated to support cardiovascular function such as Lipid Stabil , and Talos. A good liver support supplement is also a good idea since the metabolism of estrogens mainly occurs in the liver Anadrol Cycles So how much Anadrol should you use? Drugs produce a "dose-response curve" which in some cases, as with steroids like Anadrol, is a way of saying "the more you use, the more you gain.
With Anadrol we see the dose- response curve reach its ceiling flatten out fairly quickly. When you take 50mgs of Anadrol, you'll make some good gains. When you take mg of Anadrol, you'll make even bigger gains. Many who have experience with Anadrol feel that the increase from 50mg to mg constitutes an acceptable return in reward vs.
See text for additional statistical analyses 2. As you can see, in this study, doubling the dose of Anadrol 50 nearly doubled the strength gains of the test subjects.
When we look at changes in body composition from Oxymetholone chart below we can see that although the men taking mg vs. Changes in body composition are shown for the groups receiving placebo filled bars , 50 mg of oxymetholone per day open bars , and mg per day gray bars.
Anadrol can be used in a cycle at mg a day for up to 6 weeks for novices and 8 weeks for experienced users with relative safety, as long as proper Cycle Support Supplements are used in conjunction with it. Anadrol promotes quick gains in size and strength to help the user see immediate benefits in the beginning of a longer cycle usually consisting of slower acting injectable steroids like testosterone cypionate and deca-durabolin.
It would seem then that there are a lot of non-receptor mediated effects from this steroid, making it a very potent addition to any stack, because it will not be competing for the receptor sites with the other steroids you're using. Am J Obstet Gynecol. J Steroid Biochem Mol Biol. Epub Nov Last edited by ceo; at Anadrol Oxymetholone by Bill Roberts — Anadrol oxymetholone is most likely second only to Dianabol methandrostenolone as a bodybuilding anabolic steroid.
Additionally, it has had considerable medical importance particularly for treatment of anemia, and more recently to help maintain lean body mass in HIV-compromised patients. While many have the subjective opinion that Anadrol is a harsh drug in terms of side effects, medical findings and the findings of many athletes are quite different. Stacking Anadrol with Other Steroids An interesting further question concerns combination of Anadrol with other anabolic steroids.
In this its stacking behavior is similar to that of Dianabol, but not to that of trenbolone. Likely this is because unlike trenbolone, oxymetholone does not bind strongly to the androgen receptor, and most of its anabolic effect is likely not genomically mediated via the AR. Anadrol Side Effects With regard to harsh side effects sometimes perceived in bodybuilding, this principally or only occurs when estrogen levels are elevated.
While oxymetholone does not itself aromatize and does not have estrogenic activity, it may be that it can interfere with estrogen metabolism. Whether that it is the cause of the problem or not, keeping estradiol levels under control keeps Anadrol similar in side effects to other oral anabolic steroids. Estradiol levels may be kept under control either by using an aromatase inhibitor such as letrozole or Arimidex, or by limiting use of aromatizing steroids such as testosterone.
Anadrol and Liver Toxicity The principal side effect of concern is liver toxicity, as is the case for all alkylated oral anabolic steroids. This may be addressed simply by limiting duration of use to weeks, and allowing suitable time off of the drug after each period of use.
Because the liver regenerates quickly, a time of even half the period of use is often sufficient. However, allowing an equal amount of time is more conservative. Per milligram, Anadrol appears less liver toxic than any other alkylated anabolic steroid, but per amount of anabolic effect, the ratio of toxicity to anabolic effect seems similar. The same certainly cannot be said of Anavar, Dianabol, or Winstrol stanozolol.
Anadrol and Virilization This is not to say, however, that at even these reduced doses there is no risk of virilization. In these cases, any added androgen, even oral DHEA supplementation, can trigger virilizing side effects. So it must be understood that risk does exist. Using Anadrol, or Dianabol, in combination with injectable anabolic steroids is one of the most effective ways to improve a steroid cycle.
It is not necessary to use both Dianabol and Anadrol simultaneously: With proper care, side effects are generally very tolerable and pose a health risk low enough to generally be acceptable by bodybuilding standards. Oxymetholone is the name of the active ingredient in Anadrol.