The Mediterranean diet has been linked to a number of health benefits, including reduced mortality risk and lower incidence of cardiovascular. Using a microsimulation model, Oliver Mytton and colleagues estimate the health benefits of the NHS Health Check programme in the UK and. BMC Med. Jul 24; doi: / Definitions and potential health benefits of the Mediterranean diet: views from experts around.
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The team found a modest yet statistically significant protective effect of statin drugs, attributed to their ability to sensitize colorectal tumors to chemotherapy and potentially inhibit the metastatic properties of colorectal cancer. They found that simvastatin has the ability to induce tumor cell apoptosis in hepatic cancer and exert an antiproliferative effect. Further research is needed to validate this potential function of statin drugs and to pinpoint the precise mechanism of action.
According to Wood and colleagues from the University of Minnesota, the support for statin-induced neuroprotection comes in part from studies using animal models and cell culture. The authors reported that previous studies had defined several mechanisms by which statins provided benefits after traumatic brain injury.
According to the authors, statins have shown notable benefits in treating multiple sclerosis in previous experimental and preliminary clinical studies. However, based on their review, they concluded that insufficient evidence currently exists to support the use of statins as a means of treating this condition, and further randomized controlled trials are needed to clarify this relationship.
Inflammatory Disease Using statins to treat inflammatory disease may also be on the horizon. The team analyzed hyperlipidemic men and women who were randomly prescribed atorvastatin or rosuvastatin for a six-week period. Both drugs were found to be very effective in lowering LDL cholesterol and triglyceride levels in the subjects, while rosuvastatin was shown to be more effective in increasing HDL cholesterol.
Both drugs were found to significantly decrease median C-reactive protein levels; however, they also significantly increased median insulin levels from baseline. In the December issue of Aging , Japanese researchers Yudoh and Karasawa published their study examining the anti-inflammatory potential of statin drugs, focusing on their ability to prevent catabolic stress-induced chondrocyte aging and degeneration of articular cartilage in individuals with osteoarthritis.
Based on their finding, they concluded that statin medications are a potentially effective therapeutic agent for protecting articular cartilage against the progression of osteoarthritis. As published in the January issue of the American Journal of Gastroenterology , Foster and colleagues analyzed 1, men and women as part of the St. Francis Heart Study to determine whether statin therapy may be an effective treatment option for patients with nonalcoholic fatty liver disease NAFLD.
In a December issue of the Lancet , Athyros and colleagues published the Greek Atorvastatin and Coronary Heart Disease Evaluation Study, a posthoc analysis of the safety and efficacy of long-term statin therapy for cardiovascular events in patients with coronary heart disease and abnormal liver tests. Drawing from a sample of subjects with moderately abnormal liver tests at baseline, possibly associated with NAFLD, who were treated with statins showed substantial improvement in liver tests, while not treated with statins displayed further increases in liver enzyme concentrations.
The investigators concluded that statin treatment is safe and can improve liver function while reducing cardiovascular morbidity in patients with mild to moderately abnormal liver tests that may be related to NAFLD. The benefit of statins for individuals with chronic hepatitis C infection was the focus of a study by Rao and Pandya of the Kansas City Veterans Affairs Medical Center, published in the January issue of Gastroenterology.
The authors reported that people with hepatitis C are two to three times more likely to develop type 2 diabetes and thus have a lower chance of achieving a sustained virological response. The findings led the authors to conclude that statins are associated with improved sustained virological response among both diabetic and nondiabetic patients with hepatic C receiving combination antiviral treatment. Hoffman HS, et al. Management of moderate and severe alcohol withdrawal syndromes.
Alcohol use and pregnancy. Kunzmann AT, et al. The association of lifetime alcohol use with mortality and cancer risk in older adults: Vos T, et al. Alcohol use and burden for countries and territories, — A systematic analysis for the Global Burden of Disease Study Alcohol and cancer risk. Products and Services Book: Mayo Clinic on Digestive Health. Art of Healthy Eating Artificial sweeteners and other sugar substitutes Autism spectrum disorder and digestive symptoms Bad food habits at work?
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October What is Keto Diet? Reduction in Visceral Fat and on the Burden of Disease. Journal of Clinical Neurology. Good Fats and Bad Fats: The Facts on Healthy Fats. The Lowdown on Low Carb. National Multiple Sclerosis Society. The Latest in Ketogenic Diet Ketogenic Diet Microwave Keto Garlic Bread Recipe For a quick and satisfying side or breakfast that works in a restrictive keto diet, look no further than this simple recipe.
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Potential Health Benefits of Olive Oil and Plant Polyphenols.
Int J Mol Sci. Feb 28;19(3). pii: E doi: /ijms Potential Health Benefits of Olive Oil and Plant Polyphenols. Gorzynik-Debicka M(1). Now, research is pinpointing statins' potential health benefits beyond simply lowering cholesterol. This article highlights recent research suggesting that statins. The latest dietary guidelines make it clear that no one should begin drinking alcohol or drink more often on the basis of potential health benefits.